Synthesis of 6″-Modified Kanamycin A Derivatives and Evaluation of Their Antibacterial Properties

Synthesis of 6″-Modified Kanamycin A Derivatives and Evaluation of Their Antibacterial Properties

Aminoglycosides are one of the first classes of antibiotics to have been used clinically, and they are still being used today. They have a broad spectrum of antimicrobial activity, making them effective against many different types of bacteria. Despite their long history of use, aminoglycosides are...

Full description

Bibliographic Details
Main Authors: Kseniya Shapovalova, Georgy Zatonsky, Natalia Grammatikova, Ilya Osterman, Elizaveta Razumova, Andrey Shchekotikhin, Anna Tevyashova
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Pharmaceutics
Subjects:
antimicrobial resistance
aminoglycosides
kanamycin
chemical modification
mode of action
translation inhibition
Online Access:https://www.mdpi.com/1999-4923/15/4/1177

Internet

https://www.mdpi.com/1999-4923/15/4/1177

Similar Items