Network Proximity-Based Drug Repurposing Strategy for Early and Late Stages of Primary Biliary Cholangitis

Network Proximity-Based Drug Repurposing Strategy for Early and Late Stages of Primary Biliary Cholangitis

Primary biliary cholangitis (PBC) is a chronic, cholestatic, immune-mediated, and progressive liver disorder. Treatment to preventing the disease from advancing into later and irreversible stages is still an unmet clinical need. Accordingly, we set up a drug repurposing framework to find potential t...

Full description

Bibliographic Details
Main Authors: Endrit Shahini, Giuseppe Pasculli, Andrea Mastropietro, Paola Stolfi, Paolo Tieri, Davide Vergni, Raffaele Cozzolongo, Francesco Pesce, Gianluigi Giannelli
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Biomedicines
Subjects:
autoimmune liver disease
cholestatic diseases
primary biliary cirrhosis
primary sclerosing cholangitis
drug repurposing
network medicine
Online Access:https://www.mdpi.com/2227-9059/10/7/1694

Internet

https://www.mdpi.com/2227-9059/10/7/1694

Similar Items