The MCM-binding protein ETG1 aids sister chromatid cohesion required for postreplicative homologous recombination repair.
The DNA replication process represents a source of DNA stress that causes potentially spontaneous genome damage. This effect might be strengthened by mutations in crucial replication factors, requiring the activation of DNA damage checkpoints to enable DNA repair before anaphase onset. Here, we demo...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-01-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2806904?pdf=render |