Development and Validation of High-Throughput Bioanalytical Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Method for the Quantification of Newly Synthesized Antitumor Carbonic Anhydrase Inhibitors in Human Plasma

Development and Validation of High-Throughput Bioanalytical Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Method for the Quantification of Newly Synthesized Antitumor Carbonic Anhydrase Inhibitors in Human Plasma

In the present study, a sensitive and fully validated bioanalytical high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) method has been developed for the quantitative determination of three newly synthesized carbonic anhydrases inhibitors (CAIs) with potential antitumor activi...

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Bibliographic Details
Main Authors: Ahmed M. Abdel-Megied, Wagdy M. Eldehna, Mohamed A. Abdelrahman, Fawzy A. Elbarbry
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Molecules
Subjects:
LC-MS/MS
tandem mass
carbonic anhydrase inhibitors
antitumor
human plasma
bioanalytical validation
Online Access:https://www.mdpi.com/1420-3049/25/23/5753

Internet

https://www.mdpi.com/1420-3049/25/23/5753

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