Development and Validation of High-Throughput Bioanalytical Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Method for the Quantification of Newly Synthesized Antitumor Carbonic Anhydrase Inhibitors in Human Plasma

Development and Validation of High-Throughput Bioanalytical Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Method for the Quantification of Newly Synthesized Antitumor Carbonic Anhydrase Inhibitors in Human Plasma

In the present study, a sensitive and fully validated bioanalytical high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) method has been developed for the quantitative determination of three newly synthesized carbonic anhydrases inhibitors (CAIs) with potential antitumor activi...

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Bibliographic Details
Main Authors:	Ahmed M. Abdel-Megied, Wagdy M. Eldehna, Mohamed A. Abdelrahman, Fawzy A. Elbarbry
Format:	Article
Language:	English
Published:	MDPI AG 2020-12-01
Series:	Molecules
Subjects:	LC-MS/MS tandem mass carbonic anhydrase inhibitors antitumor human plasma bioanalytical validation
Online Access:	https://www.mdpi.com/1420-3049/25/23/5753

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