Innate and Adaptive Responses of Intratumoral Immunotherapy with Endosomal Toll-Like Receptor Agonists

Toll-like receptors (TLRs) are natural initial triggers of innate and adaptive immune responses. With the advent of cancer immunotherapy, nucleic acids engineered as ligands of endosomal TLRs have been investigated for the treatment of solid tumors. Despite promising results, their systemic administ...

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Detalhes bibliográficos
Principais autores: Fernando Torres Andón, Sergio Leon, Aldo Ummarino, Esther Redin, Paola Allavena, Diego Serrano, Clément Anfray, Alfonso Calvo
Formato: Artigo
Idioma:English
Publicado em: MDPI AG 2022-07-01
coleção:Biomedicines
Assuntos:
Acesso em linha:https://www.mdpi.com/2227-9059/10/7/1590