Membrane recruitment of the polarity protein Scribble by the cell adhesion receptor TMIGD1

Membrane recruitment of the polarity protein Scribble by the cell adhesion receptor TMIGD1

Abstract Scribble (Scrib) is a multidomain polarity protein and member of the leucine-rich repeat and PDZ domain (LAP) protein family. A loss of Scrib expression is associated with disturbed apical-basal polarity and tumor formation. The tumor-suppressive activity of Scrib correlates with its membra...

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Bibliographic Details
Main Authors: Eva-Maria Thüring, Christian Hartmann, Janesha C. Maddumage, Airah Javorsky, Birgitta E. Michels, Volker Gerke, Lawrence Banks, Patrick O. Humbert, Marc Kvansakul, Klaus Ebnet
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05088-3

Internet

https://doi.org/10.1038/s42003-023-05088-3

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