The Progressive Mutagenic Effects of Acidic Bile Refluxate in Hypopharyngeal Squamous Cell Carcinogenesis: New Insights
Cancers of the laryngopharynx represent the most devastating of the head and neck malignancies and additional risk factors are now epidemiologically linked to this disease. Using an in vivo model (<i>Mus musculus</i> C57Bl/6J), we provide novel evidence that acidic bile (pH 3.0) progress...
Main Authors: | Clarence T. Sasaki, Sotirios G. Doukas, Jose Costa, Dimitra P. Vageli |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-04-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/12/5/1064 |
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