Identification of a DNA methylome profile of esophageal squamous cell carcinoma and potential plasma epigenetic biomarkers for early diagnosis.

DNA methylation is a critical epigenetic mechanism involved in key cellular processes. Its deregulation has been linked to many human cancers including esophageal squamous cell carcinoma (ESCC). This study was designed to explore the whole methylation status of ESCC and to identify potential plasma...

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Bibliographic Details
Main Authors: Xufeng Li, Fuyou Zhou, Chunyu Jiang, Yinuo Wang, Yanqiang Lu, Fei Yang, Nengchao Wang, Haijun Yang, Yanfang Zheng, Jiren Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4106874?pdf=render