The Consequences of Mitochondrial T10432C Mutation in Cika Cattle: A “Potential” Model for Leber’s Hereditary Optic Neuropathy

The Consequences of Mitochondrial T10432C Mutation in Cika Cattle: A “Potential” Model for Leber’s Hereditary Optic Neuropathy

While mitogenome mutations leading to pathological manifestations are rare, more than 200 such mutations have been described in humans. In contrast, pathogenic mitogenome mutations are rare in domestic animals and have not been described at all in cattle. In the small local Slovenian cattle breed Ci...

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Bibliographic Details
Main Authors: Dinko Novosel, Vladimir Brajković, Mojca Simčič, Minja Zorc, Tanja Svara, Karmen Branovic Cakanic, Andreja Jungić, Betka Logar, Vlatka Cubric-Curik, Peter Dovc, Ino Curik
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
animal model
retinal ablation
cattle
detrimental mutations
LHON
mitogenome
Online Access:https://www.mdpi.com/1422-0067/23/11/6335

Internet

https://www.mdpi.com/1422-0067/23/11/6335

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