Real-World Data on Cabozantinib in Advanced Osteosarcoma and Ewing Sarcoma Patients: A Study from the Hellenic Group of Sarcoma and Rare Cancers

Real-World Data on Cabozantinib in Advanced Osteosarcoma and Ewing Sarcoma Patients: A Study from the Hellenic Group of Sarcoma and Rare Cancers

Advanced osteosarcomas (OSs) and Ewing sarcomas (ESs) tend to have poor prognosis with limited therapeutic options beyond first-line therapy. Aberrant angiogenesis and MET signaling play an important role in preclinical models. The anti-angiogenic drug cabozantinib was tested in a phase 2 trial of a...

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Bibliographic Details
Main Authors: Stefania Kokkali, Anastasios Kyriazoglou, Elpida Mangou, Panagiota Economopoulou, Michail Panousieris, Amanda Psyrri, Alexandros Ardavanis, Nikolaos Vassos, Ioannis Boukovinas
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Journal of Clinical Medicine
Subjects:
osteosarcoma
Ewing sarcoma
bone sarcoma
cabozantinib
tyrosine kinase inhibitor
Online Access:https://www.mdpi.com/2077-0383/12/3/1119

Internet

https://www.mdpi.com/2077-0383/12/3/1119

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