Expanding the Editing Window of Cytidine Base Editors With the Rad51 DNA-Binding Domain in Rice

Recently developed base editors provide a powerful tool for plant research and crop improvement. Although a number of different deaminases and Cas proteins have been used to improve base editors the editing efficiency, and editing window are still not optimal. Fusion of a non-sequence-specific singl...

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Bibliographic Details
Main Authors: Chunjie Wei, Hao Liu, Wenwen Wang, Pengyu Luo, Qiuling Chen, Rou Li, Chong Wang, José Ramón Botella, Hui Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Plant Science
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpls.2022.865848/full