Peripheral inflammation is associated with brain atrophy and cognitive decline linked to mild cognitive impairment and Alzheimer’s disease

Peripheral inflammation is associated with brain atrophy and cognitive decline linked to mild cognitive impairment and Alzheimer’s disease

Abstract Inflammation is an important factor in Alzheimer’s disease (AD). An NMR measurement in plasma, glycoprotein acetyls (GlycA), captures the overall level of protein production and glycosylation implicated in systemic inflammation. With its additional advantage of reducing biological variabili...

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Bibliographic Details
Main Authors: Nuanyi Liang, Kwangsik Nho, John W. Newman, Matthias Arnold, Kevin Huynh, Peter J. Meikle, Kamil Borkowski, Rima Kaddurah-Daouk, the Alzheimer’s Disease Metabolomics Consortium
Format: Article
Language:English
Published: Nature Portfolio 2024-07-01
Series:Scientific Reports
Subjects:
Alzheimer’s disease
Mild cognitive impairment
GlycA
Inflammation
Inflammatory biomarker
Metabolomics
Online Access:https://doi.org/10.1038/s41598-024-67177-5

Internet

https://doi.org/10.1038/s41598-024-67177-5

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