Mitochondrial function and oxidative stress in white adipose tissue in a rat model of PCOS: effect of SGLT2 inhibition

Mitochondrial function and oxidative stress in white adipose tissue in a rat model of PCOS: effect of SGLT2 inhibition

Highlights 1. Androgen excess in PCOS model is associated with decreased markers of mitochondrial content in both subcutaneous and visceral white adipose tissue. 2. Androgen excess in PCOS model is associated with increased frequency of small adipocytes in subcutaneous white adipose tissue while dec...

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Bibliographic Details
Main Authors: Jacob E. Pruett, Steven J. Everman, Ngoc H. Hoang, Faridah Salau, Lucy C. Taylor, Kristin S. Edwards, Jonathan P. Hosler, Alexandra M. Huffman, Damian G. Romero, Licy L. Yanes Cardozo
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Biology of Sex Differences
Subjects:
Polycystic ovary syndrome
Androgens
Mitochondrial dysfunction
White adipose tissue
Sodium–glucose cotransporter-2
Online Access:https://doi.org/10.1186/s13293-022-00455-x

Internet

https://doi.org/10.1186/s13293-022-00455-x

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