Mitochondrial function and oxidative stress in white adipose tissue in a rat model of PCOS: effect of SGLT2 inhibition

Mitochondrial function and oxidative stress in white adipose tissue in a rat model of PCOS: effect of SGLT2 inhibition

Highlights 1. Androgen excess in PCOS model is associated with decreased markers of mitochondrial content in both subcutaneous and visceral white adipose tissue. 2. Androgen excess in PCOS model is associated with increased frequency of small adipocytes in subcutaneous white adipose tissue while dec...

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Dettagli Bibliografici
Autori principali: Jacob E. Pruett, Steven J. Everman, Ngoc H. Hoang, Faridah Salau, Lucy C. Taylor, Kristin S. Edwards, Jonathan P. Hosler, Alexandra M. Huffman, Damian G. Romero, Licy L. Yanes Cardozo
Natura: Articolo
Lingua:English
Pubblicazione: BMC 2022-08-01
Serie:Biology of Sex Differences
Soggetti:
Polycystic ovary syndrome
Androgens
Mitochondrial dysfunction
White adipose tissue
Sodium–glucose cotransporter-2
Accesso online:https://doi.org/10.1186/s13293-022-00455-x

Accesso online

https://doi.org/10.1186/s13293-022-00455-x

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