Anti-Amyloidogenic Properties of Some Phenolic Compounds

A family of 21 polyphenolic compounds consisting of those found naturally in danshen and their analogues were synthesized and subsequently screened for their anti-amyloidogenic activity against the amyloid beta peptide (Aβ42) of Alzheimer’s disease. After 24 h incubation with Aβ42, five compounds...

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Bibliographic Details
Main Authors: Afsaneh Porzoor, Benjamin Alford, Helmut M. Hügel, Danilla Grando, Joanne Caine, Ian Macreadie
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:Biomolecules
Subjects:
Online Access:http://www.mdpi.com/2218-273X/5/2/505