Molecular docking and in vitro anticancer studies of silver(I)-N-heterocyclic carbene complexes

A series of symmetric and unsymmetrical benzimidazolium-based N-heterocyclic carbene (NHC) precursors (1a-i) and their silver complexes (2a-i) have been synthesized. The Ag(I)–NHC complexes were characterized by 1H, 13C{1H} NMR, FTIR, LC/MS-QTOF, and elemental analysis. Anticancer and cytotoxic acti...

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Bibliographic Details
Main Authors: Mitat Akkoç, Siraj Khan, Hande Yüce, Neşe Başak Türkmen, Şeyma Yaşar, Sedat Yaşar, İsmail Özdemir
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022014219