Delineation of renal protein profiles in aristolochic acid I-induced nephrotoxicity in mice by label-free quantitative proteomics

Introduction: Aristolochic acid nephropathy (AAN) is a kidney injury syndrome caused by aristolochic acids exposure. Our study used label-free quantitative proteomics to delineate renal protein profiles and identify key proteins after exposure to different doses of aristolochic acid I (AAI).Methods:...

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Bibliographic Details
Main Authors: Xinhui Liu, Shanshan Wu, Yu Peng, Liwen Gao, Xi Huang, Ruyu Deng, Jiandong Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-05-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1341854/full