The Potential Role of Curcumin in Modulating the Master Antioxidant Pathway in Diabetic Hypoxia-Induced Complications

The Potential Role of Curcumin in Modulating the Master Antioxidant Pathway in Diabetic Hypoxia-Induced Complications

Oxidative stress is the leading player in the onset and development of various diseases. The Keap1-Nrf2 pathway is a pivotal antioxidant system that preserves the cells’ redox balance. It decreases inflammation in which the nuclear trans-localization of Nrf2 as a transcription factor promotes variou...

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Bibliographic Details
Main Authors: Somayyeh Ghareghomi, Mahdie Rahban, Zainab Moosavi-Movahedi, Mehran Habibi-Rezaei, Luciano Saso, Ali Akbar Moosavi-Movahedi
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Molecules
Subjects:
Keap1-Nrf2
diabetes
oxidative stress
curcumin
antioxidant enzymes
hypoxia-inducible factor 1 (HIF-1)
Online Access:https://www.mdpi.com/1420-3049/26/24/7658

Internet

https://www.mdpi.com/1420-3049/26/24/7658

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