Proteins with complex architecture as potential targets for drug design: a case study of Mycobacterium tuberculosis.

Lengthy co-evolution of Homo sapiens and Mycobacterium tuberculosis, the main causative agent of tuberculosis, resulted in a dramatically successful pathogen species that presents considerable challenge for modern medicine. The continuous and ever increasing appearance of multi-drug resistant mycoba...

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Bibliographic Details
Main Authors: Bálint Mészáros, Judit Tóth, Beáta G Vértessy, Zsuzsanna Dosztányi, István Simon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-07-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002118&type=printable