Cigarette Smoke-Induced Lymphoid Neogenesis in COPD Involves IL-17/RANKL Pathway

Cigarette Smoke-Induced Lymphoid Neogenesis in COPD Involves IL-17/RANKL Pathway

IL-17 is critical in lung lymphoid neogenesis in COPD, but the cellular and molecular mechanisms remain to be elucidated. Receptor activator of nuclear factor-κB ligand (RANKL) functions in lymphoid follicle formation in other organs, whether it is involved in IL-17A–dependent lymphoid neogenesis in...

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Bibliographic Details
Main Authors: Jing Xiong, Lu Zhou, Jieyu Tian, Xia Yang, Yunsong Li, Rong Jin, Yanqing Le, Yafei Rao, Yongchang Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
chronic obstructive pulmonary disease
lymphoid follicles
interleukin 17
receptor activator of nuclear factor-κB ligand
RANK
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.588522/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.588522/full

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