Role of RAS signaling in ovarian cancer [version 1; peer review: 2 approved]
The RAS family of proteins is among the most frequently mutated genes in human malignancies. In ovarian cancer (OC), the most lethal gynecological malignancy, RAS, especially KRAS mutational status at codons 12, 13, and 61, ranges from 6–65% spanning different histo-types. Normally RAS regulates sev...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2022-11-01
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Series: | F1000Research |
Subjects: | |
Online Access: | https://f1000research.com/articles/11-1253/v1 |