Role of RAS signaling in ovarian cancer [version 1; peer review: 2 approved]

Role of RAS signaling in ovarian cancer [version 1; peer review: 2 approved]

The RAS family of proteins is among the most frequently mutated genes in human malignancies. In ovarian cancer (OC), the most lethal gynecological malignancy, RAS, especially KRAS mutational status at codons 12, 13, and 61, ranges from 6–65% spanning different histo-types. Normally RAS regulates sev...

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Bibliographic Details
Main Authors: Hesham M. Korashy, Shahab Uddin, Abdullah Azmi, Ajaz Bhat, Lubna Therachiyil, Anjana Anand
Format: Article
Language:English
Published: F1000 Research Ltd 2022-11-01
Series:F1000Research
Subjects:
Ovarian cancers
RAS
Oncogene
mutation
cell signaling
eng
Online Access:https://f1000research.com/articles/11-1253/v1

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