Multisite dependency of an E3 ligase controls monoubiquitylation-dependent cell fate decisions

Multisite dependency of an E3 ligase controls monoubiquitylation-dependent cell fate decisions

Metazoan development depends on tightly regulated gene expression programs that instruct progenitor cells to adopt specialized fates. Recent work found that posttranslational modifications, such as monoubiquitylation, can determine cell fate also independently of effects on transcription, yet how mo...

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Bibliographic Details
Main Authors: Achim Werner, Regina Baur, Nia Teerikorpi, Deniz U Kaya, Michael Rape
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-07-01
Series:eLife
Subjects:
ubiquitin
CUL3
neural crest
CK2
multisite phosphorylation
monoubiquitylation
Online Access:https://elifesciences.org/articles/35407

Internet

https://elifesciences.org/articles/35407

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