3-Nitroatenolol: First Synthesis, Chiral Resolution and Enantiomers’ Absolute Configuration

3-Nitroatenolol: First Synthesis, Chiral Resolution and Enantiomers’ Absolute Configuration

4-Nitro and 7-nitro propranolol have been recently synthesized and characterized by us. (±)-4-NO<sub>2</sub>-propranolol has been shown to act as a selective antagonist of 6-nitrodopamine (6-ND) receptors in the right atrium of rats. As part of our follow-up to this study, herein, we des...

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Bibliographic Details
Main Authors: Rosa Sparaco, Pierfrancesco Cinque, Antonia Scognamiglio, Angela Corvino, Giuseppe Caliendo, Ferdinando Fiorino, Elisa Magli, Elisa Perissutti, Vincenzo Santagada, Beatrice Severino, Paolo Luciano, Marcello Casertano, Anna Aiello, Gustavo Yuri Martins Viegas, Gilberto De Nucci, Francesco Frecentese
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:Molecules
Subjects:
3-nitroatenolol
chiral HPLC
NMR absolute configuration assignment
Riguera’s method
Online Access:https://www.mdpi.com/1420-3049/29/7/1598

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https://www.mdpi.com/1420-3049/29/7/1598

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