Warfarin dosage response related pharmacogenetics in Chinese population.

OBJECTIVES:As the most frequently prescribed anticoagulant, warfarin has large inter-individual variability in dosage. Genetic polymorphisms could largely explain the differences in dosage requirement. rs9923231 (VKORC1), rs7294 (VKORC1), rs1057910 (CYP2C9), rs2108622 (CYP4F2), and rs699664 (GGCX) i...

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Bibliographic Details
Main Authors: Siyue Li, Yuangao Zou, Xia Wang, Xunbei Huang, Yong Sun, Yuqing Wang, Li Dong, Hong Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4296935?pdf=render