Quantitative ChIP-Seq Normalization Reveals Global Modulation of the Epigenome

Quantitative ChIP-Seq Normalization Reveals Global Modulation of the Epigenome

Epigenomic profiling by chromatin immunoprecipitation coupled with massively parallel DNA sequencing (ChIP-seq) is a prevailing methodology used to investigate chromatin-based regulation in biological systems such as human disease, but the lack of an empirical methodology to enable normalization amo...

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Bibliographic Details
Main Authors: David A. Orlando, Mei Wei Chen, Victoria E. Brown, Snehakumari Solanki, Yoon J. Choi, Eric R. Olson, Christian C. Fritz, James E. Bradner, Matthew G. Guenther
Format: Article
Language:English
Published: Elsevier 2014-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714008729

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http://www.sciencedirect.com/science/article/pii/S2211124714008729

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