Establishment and Characterization of a HER2-Positive Cell Line Derived From the Pleural Effusion of a Drug-Resistant Breast Cancer Patient

Establishment and Characterization of a HER2-Positive Cell Line Derived From the Pleural Effusion of a Drug-Resistant Breast Cancer Patient

Drug resistance is a daunting challenge in the treatment of breast cancer, making it an urgent problem to solve in studies. Cell lines are important tools in basic and preclinical studies; however, few breast cell lines from drug-resistant patients are available. Herein, we established a novel HER2-...

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Bibliographic Details
Main Authors: Zhaoqing Li, Wenying Zhuo, Lini Chen, Xun Zhang, Cong Chen, Dengdi Hu, Yongxia Chen, Jingjing Yang, Yulu Zhou, Misha Mao, Ling Xu, Siwei Ju, Jun Shen, Qinchuan Wang, Minjun Dong, Shuduo Xie, Jichun Zhou, Linbo Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
breast cancer cell line 4Z-B-1
HER2-positive
invasive ductal breast carcinoma
metastatic
HER2 targeting
phenotype change
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.680968/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.680968/full

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