Plasma metabolomic and lipidomic alterations associated with anti-tuberculosis drug-induced liver injury

Background: Anti-tuberculosis drug-induced liver injury (ATB-DILI) is an adverse reaction with a high incidence and the greatest impact on tuberculosis treatment. However, there is a lack of effective biomarkers for the early prediction of ATB-DILI. Herein, this study uses UPLC‒MS/MS to reveal the p...

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Bibliographic Details
Main Authors: Ming-Gui Wang, Shou-Quan Wu, Meng-Meng Zhang, Jian-Qing He
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1044808/full