Two RhoGEF isoforms with distinct localisation control furrow position during asymmetric cell division

Abstract Cytokinesis partitions cellular content between daughter cells. It relies on the formation of an acto-myosin contractile ring, whose constriction induces the ingression of the cleavage furrow between the segregated chromatids. Rho1 GTPase and its RhoGEF (Pbl) are essential for this process....

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Bibliographic Details
Main Authors: Emilie Montembault, Irène Deduyer, Marie-Charlotte Claverie, Lou Bouit, Nicolas J. Tourasse, Denis Dupuy, Derek McCusker, Anne Royou
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-38912-9