ZIKV infection activates the IRE1-XBP1 and ATF6 pathways of unfolded protein response in neural cells

ZIKV infection activates the IRE1-XBP1 and ATF6 pathways of unfolded protein response in neural cells

Abstract Background Many viruses depend on the extensive membranous network of the endoplasmic reticulum (ER) for their translation, replication, and packaging. Certain membrane modifications of the ER can be a trigger for ER stress, as well as the accumulation of viral protein in the ER by viral in...

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Bibliographic Details
Main Authors: Zhongyuan Tan, Wanpo Zhang, Jianhong Sun, Zuquan Fu, Xianliang Ke, Caishang Zheng, Yuan Zhang, Penghui Li, Yan Liu, Qinxue Hu, Hanzhong Wang, Zhenhua Zheng
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Journal of Neuroinflammation
Subjects:
Zika virus
Neural cell
Neuropathogenesis
ER stress
Unfolded protein response
Online Access:http://link.springer.com/article/10.1186/s12974-018-1311-5

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http://link.springer.com/article/10.1186/s12974-018-1311-5

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