Autocatalytic microtubule nucleation determines the size and mass of Xenopus laevis egg extract spindles
Regulation of size and growth is a fundamental problem in biology. A prominent example is the formation of the mitotic spindle, where protein concentration gradients around chromosomes are thought to regulate spindle growth by controlling microtubule nucleation. Previous evidence suggests that micro...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2018-01-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/31149 |