ERRγ Promotes Angiogenesis, Mitochondrial Biogenesis, and Oxidative Remodeling in PGC1α/β-Deficient Muscle

ERRγ Promotes Angiogenesis, Mitochondrial Biogenesis, and Oxidative Remodeling in PGC1α/β-Deficient Muscle

Summary: PGC1α is a pleiotropic co-factor that affects angiogenesis, mitochondrial biogenesis, and oxidative muscle remodeling via its association with multiple transcription factors, including the master oxidative nuclear receptor ERRγ. To decipher their epistatic relationship, we explored ERRγ gai...

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Bibliographic Details
Main Authors: Weiwei Fan, Nanhai He, Chun Shi Lin, Zong Wei, Nasun Hah, Wanda Waizenegger, Ming-Xiao He, Christopher Liddle, Ruth T. Yu, Annette R. Atkins, Michael Downes, Ronald M. Evans
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718302286

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http://www.sciencedirect.com/science/article/pii/S2211124718302286

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