Engineering the conserved and noncatalytic residues of a thermostable β-1,4-endoglucanase to improve specific activity and thermostability

Abstract Endoglucanases are increasingly applied in agricultural and industrial applications as a key biocatalyst for cellulose biodegradation. However, the low performance in extreme conditions seriously challenges the enzyme’s commercial utilization. To obtain endoglucanases with substantially imp...

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Bibliographic Details
Main Authors: Xiutao Chen, Weiguang Li, Peng Ji, Yang Zhao, Chengyao Hua, Chao Han
Format: Article
Language:English
Published: Nature Portfolio 2018-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-21246-8