Autotrophic growth of Escherichia coli is achieved by a small number of genetic changes

Autotrophic growth of Escherichia coli is achieved by a small number of genetic changes

Synthetic autotrophy is a promising avenue to sustainable bioproduction from CO2. Here, we use iterative laboratory evolution to generate several distinct autotrophic strains. Utilising this genetic diversity, we identify that just three mutations are sufficient for Escherichia coli to grow autotrop...

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Bibliographic Details
Main Authors: Roee Ben Nissan, Eliya Milshtein, Vanessa Pahl, Benoit de Pins, Ghil Jona, Dikla Levi, Hadas Yung, Noga Nir, Dolev Ezra, Shmuel Gleizer, Hannes Link, Elad Noor, Ron Milo
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-02-01
Series:eLife
Subjects:
synthetic autotrophy
metabolic rewiring
carbon fixation
sustainability
Online Access:https://elifesciences.org/articles/88793

Internet

https://elifesciences.org/articles/88793

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