Therapeutic potential of MCC950, a specific inhibitor of NLRP3 inflammasome in systemic lupus erythematosus

Therapeutic potential of MCC950, a specific inhibitor of NLRP3 inflammasome in systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is a complex autoimmune disorder with a pathogenesis that remains incompletely understood, resulting in limited treatment options. MCC950, a highly specific NLRP3 inflammasome inhibitor, effectively suppresses the activation of NLRP3, thus reducing the production o...

Full description

Bibliographic Details
Main Authors: Xiaoxiao Wu, Junhao Yang, Juanjie Wu, Xuyan Yang
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
MCC950
Systemic lupus erythematosus
NLRP3 inflammasome
Therapeutic mechanism
Autoimmune disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332224001422

Internet

http://www.sciencedirect.com/science/article/pii/S0753332224001422

Similar Items