PON-Sol2: Prediction of Effects of Variants on Protein Solubility

Genetic variations have a multitude of effects on proteins. A substantial number of variations affect protein–solvent interactions, either aggregation or solubility. Aggregation is often related to structural alterations, whereas solubilizable proteins in the solid phase can be made again soluble by...

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Bibliographic Details
Main Authors: Yang Yang, Lianjie Zeng, Mauno Vihinen
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/15/8027