Progress study on the mechanism of CAG repeats dynamic mutation in polyQ disease
Polyglutamine (polyQ) disease is a group of neurodegenerative disorders caused by abnormal expansion of CAG repeats within coding regions of certain causative genes, which are translated into a series of abnormally expanded polyQ tracts causing cytotoxicity. So far, nine diseases caused by expanded...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Tianjin Huanhu Hospital
2012-06-01
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| Series: | Chinese Journal of Contemporary Neurology and Neurosurgery |
| Subjects: | |
| Online Access: | http://www.cjcnn.org/index.php/cjcnn/article/view/351 |