A novel eukaryotic RdRP-dependent small RNA pathway represses antiviral immunity by controlling an ERK pathway component in the black-legged tick

A novel eukaryotic RdRP-dependent small RNA pathway represses antiviral immunity by controlling an ERK pathway component in the black-legged tick

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Small regulatory RNAs (sRNAs) are involved in antiviral defense and gene regulation. Although roles of RNA-dependent RNA Polymerases (RdRPs) in sRNA biology are extensively studied in nematodes, plants and fungi, understanding of RdRP homologs in other animals is still lacking. Here, we study sRNAs...

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Bibliographic Details
Main Authors: Canran Feng, Kyosuke Torimaru, Mandy Yu Theng Lim, Li-Ling Chak, Masami Shiimori, Kosuke Tsuji, Tetsuya Tanaka, Junko Iida, Katsutomo Okamura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062562/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062562/?tool=EBI

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