XBP1 inhibits mesangial cell apoptosis in response to oxidative stress via the PTEN/AKT pathway in diabetic nephropathy

XBP1 inhibits mesangial cell apoptosis in response to oxidative stress via the PTEN/AKT pathway in diabetic nephropathy

Diabetic nephropathy (DN) is a complication of diabetes mellitus (DM) that frequently results in renal disease, and is characterized by a variety of symptoms, including albuminuria. It has been shown that apoptosis of glomerular mesangial cells (MCs) can aggravate albuminuria and contribute to the d...

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Bibliographic Details
Main Authors: Yan Wang, Zhong He, Qiu Yang, Guangju Zhou
Format: Article
Language:English
Published: Wiley 2019-07-01
Series:FEBS Open Bio
Subjects:
apoptosis
mesangial cell
oxidative stress
PTEN/AKT pathway
XBP1
Online Access:https://doi.org/10.1002/2211-5463.12655

Internet

https://doi.org/10.1002/2211-5463.12655

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