Isocyanide Multicomponent Reactions on Solid Phase: State of the Art and Future Application

Isocyanide Multicomponent Reactions on Solid Phase: State of the Art and Future Application

Drug discovery efforts largely depend on access to structural diversity. Multicomponent reactions allow for time-efficient chemical transformations and provide advanced intermediates with three or four points of diversification for further expansion to a structural variety of organic molecules. This...

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Bibliographic Details
Main Authors: Naděžda Cankařová, Viktor Krchňák
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
convertible isocyanides
drug discovery
multicomponent reactions
post-Ugi transformations
solid-phase synthesis
Ugi four-component reaction
Online Access:https://www.mdpi.com/1422-0067/21/23/9160

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https://www.mdpi.com/1422-0067/21/23/9160

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