Molecular Anatomy of the Class I Ligase Ribozyme for Elucidation of the Activity-Generating Unit

The class I ligase ribozyme consists of 121 nucleotides and shows a high catalytic rate comparable to that found in natural proteinaceous polymerases. In this study, we aimed to identify the smaller active unit of the class I ligase ribozyme comprising ~50 nucleotides, comparable to the estimated le...

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Bibliographic Details
Main Authors: Miho Kasuga, Hiromi Mutsuro-Aoki, Tadashi Ando, Koji Tamura
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/12/7/1012