Taxifolin alleviate metabolic and neurochemical alterations in the hippocampus and cortex of rats with rotenone-induced toxicity: In vivo and in silico insight

Taxifolin alleviate metabolic and neurochemical alterations in the hippocampus and cortex of rats with rotenone-induced toxicity: In vivo and in silico insight

Introduction: Exposure to rotenone could directly affects the function of mitochondrial which leads to neurodegeneration. This study evaluated the therapeutic potential of taxifolin (Huāqí sōng dài; 花旗松甙) to alleviate metabolic and neurochemical alterations in the hippocampal and cortical region of...

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Bibliographic Details
Main Authors: Courage Dele Famusiwa, Sunday Solomon Josiah, Ibrahim Olabayode Saliu, Toluwase Hezekiah Fatoki, Haruna Isiyaku Umar, Afolabi Clement Akinmoladun
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Pharmacological Research - Modern Chinese Medicine
Subjects:
Rotenone
Antioxidants
Taxifolin
Neurotoxicity
Oxidative stress
Metabolic dysregulation
Online Access:http://www.sciencedirect.com/science/article/pii/S2667142524000824

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http://www.sciencedirect.com/science/article/pii/S2667142524000824

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