Modeling the Competition between Misfolded Aβ Conformers That Produce Distinct Types of Amyloid Pathology in Alzheimer’s Disease

The amyloid pathology characteristic of Alzheimer’s disease (AD) can be broadly classified as either fibrillary amyloid or diffuse amyloid. Fibrillary amyloid is found in cored-neuritic deposits, fibrillar deposits, and vascular deposits, and binds strongly to the amyloid revealing dyes Thioflavin-S...

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Bibliografiska uppgifter
Huvudupphovsmän: Guilian Xu, Susan Fromholt, David R. Borchelt
Materialtyp: Artikel
Språk:English
Publicerad: MDPI AG 2022-06-01
Serie:Biomolecules
Ämnen:
Länkar:https://www.mdpi.com/2218-273X/12/7/886