The Warburg Trap: A Novel Therapeutic Approach for Targeting Osteosarcoma

Although urgently needed, no significant improvements in osteosarcoma (OS) therapy have been achieved within the last decades. Here, we present a new therapeutic approach based on drug combinations consisting of mitochondrial complex I (MCI) inhibitors and ionophores that induce cancer cell-specific...

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Bibliographic Details
Main Authors: Joerg Fellenberg, Sarina Losch, Elena Tripel, Burkhard Lehner, Svitlana Melnik
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/13/1/61