Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli
Nucleotide excision repair is able to identify and remove a wide range of DNA helix distorting lesions from the genome. Here the authors use single molecule imaging of UvrA and UvrB molecules and suggest a two-step ‘scan and recruit’ model for UvrA function.
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2016-08-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms12568 |