Experimental Hut Trials Reveal That CYP6P9a/b P450 Alleles Are Reducing the Efficacy of Pyrethroid-Only Olyset Net against the Malaria Vector <i>Anopheles funestus</i> but PBO-Based Olyset Plus Net Remains Effective

Experimental Hut Trials Reveal That CYP6P9a/b P450 Alleles Are Reducing the Efficacy of Pyrethroid-Only Olyset Net against the Malaria Vector <i>Anopheles funestus</i> but PBO-Based Olyset Plus Net Remains Effective

Malaria remains a major public health concern in Africa. Metabolic resistance in major malaria vectors such as <i>An. funestus</i> is jeopardizing the effectiveness of long-lasting insecticidal nets (LLINs) to control malaria. Here, we used experimental hut trials (EHTs) to investigate t...

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Bibliographic Details
Main Authors: Benjamin D. Menze, Leon M. J. Mugenzi, Magellan Tchouakui, Murielle J. Wondji, Micareme Tchoupo, Charles S. Wondji
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Pathogens
Subjects:
malaria
long-lasting insecticidal nets
insecticide resistance
metabolic resistance
cytochrome P450
<i>Anopheles funestus</i>
Online Access:https://www.mdpi.com/2076-0817/11/6/638

Internet

https://www.mdpi.com/2076-0817/11/6/638

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