PPAR agonists as add-on treatment with metformin in management of type 2 diabetes: a systematic review and meta-analysis

PPAR agonists as add-on treatment with metformin in management of type 2 diabetes: a systematic review and meta-analysis

Abstract The combination of metformin and the peroxisome proliferator-activated receptors (PPAR) agonists offers a promising avenue for managing type 2 diabetes (T2D) through their potential complementary mechanisms of action. The results from randomized controlled trials (RCT) assessing the efficac...

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Bibliographic Details
Main Authors: Saif Alnuaimi, Tea Reljic, Fatima S. Abdulla, Hamda Memon, Sarah Al-Ali, Teagen Smith, Fadila Serdarevic, Zelija Velija Asimi, Ambuj Kumar, Sabina Semiz
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Scientific Reports
Subjects:
Glycemic control
Insulin resistance
Lipids
Safety profile
Gastrointestinal intolerance
Online Access:https://doi.org/10.1038/s41598-024-59390-z

Internet

https://doi.org/10.1038/s41598-024-59390-z

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