The synaptic scaffold protein MPP2 interacts with GABAA receptors at the periphery of the postsynaptic density of glutamatergic synapses.

Recent advances in imaging technology have highlighted that scaffold proteins and receptors are arranged in subsynaptic nanodomains. The synaptic membrane-associated guanylate kinase (MAGUK) scaffold protein membrane protein palmitoylated 2 (MPP2) is a component of α-amino-3-hydroxy-5-methyl-4-isoxa...

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Main Authors: Bettina Schmerl, Niclas Gimber, Benno Kuropka, Alexander Stumpf, Jakob Rentsch, Stella-Amrei Kunde, Judith von Sivers, Helge Ewers, Dietmar Schmitz, Christian Freund, Jan Schmoranzer, Nils Rademacher, Sarah A Shoichet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-03-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001503