Semisynthesis of Taxol®: an improved procedure for the isolation of 10-deacetylbaccatin III
From the needles of domestic yew, (Taxus baccata), 10-deacetylbaccatin III (10-DAB) can be isolated in quantities of up to 297 mg per kg of fresh needles. Additional quantities of 10-DAB can be obtained from the extract by NaBH4 mediated reductive hydrolysis of baccatin esters. A four-step procedure...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Serbian Chemical Society
1999-09-01
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| Series: | Journal of the Serbian Chemical Society |
| Subjects: | |
| Online Access: | http://www.shd.org.yu/HtDocs/SHD/Vol64/No9-Pdf/V64-no9-01.zip |